From Attention to Goal-Directed Behavior: Neurodynamical, Methodological and Clinical Trends

The authors present an updated view of neurodynamical approaches to attentional mechanisms and related percetual and consicousness questions with a take on neuropsychiatric illnesses which can shed light on these problems, specifically ADHD and schizophrenia. Furthermore, they provide novel evidence pointing to genetic and neurochemical factors as important elements determining individual diversity in neurodynamical patterns, and susceptibility to mental disease. Thus the authors present a combined neurodynamic, cognitive, neurochemical and genetic perspective that is rarely attempted in reviews on this topic. To do so they focus and develop a number of specific exemplary issues avoiding a too general review perspective so as to provide an in-depth view into the mechanisms involved.

This volume presents an updated view of neurodynamical approaches to attentional mechanisms and related percetual and consciousness questions with a take on neuropsychiatric illnesses which can shed light on these problems, specifically ADHD and schizophrenia

I. Attentional Networks: basic mechanisms and methodological issues.- 1. Neuronal signatures of selective attention: Synchronization and gain modulation as mechanisms for selective sensory information processing.- 2. Intracortical recordings during attentional tasks.- 3. The Spatiotemporal Dynamics of Visual-Spatial Attention.- 4. Attention and neurodynamical correlates of natural vision.- 5. Attending to the Stream of Consciousness: A Methodological Challenge.- 6. Crossmodal Attention: the contribution of event-related potential studies.- 7. Measuring and Modulating Hemispheric Attention.- 8. A connectionist perspective on attentional effects in neurodynamics data.- II. From Attention to Behavioral Control.- 9. From goals to habits: a view from the network.- 10. Dynamics of a neuromodulator: I. The role of dopaminergic signaling in goal-directed behavior.- 1. Dynamics of a neuromodulator: II. Dopaminergic balance and cognition.- III. Clinical and Developmental Issues.- 12. Prefrontal cortex and control of behavior: Evidence from neuropsychological studies.- 13. The Maturation of Cognitive Control and the Adolescent Brain.- 14. Electrophysiological and genetic markers of attentional deficit-hyperactivity disorder (ADHD): boundary conditions for normal attentional processing.- 15. The aberrant connectivity hypothesis in schizophrenia.- Subject Index.

Francisco Aboitiz earned a PhD in Neuroscience at UCLA in 1991 analyizing the fiber composition of the human corpus callosum. After a period of postdoctoral training in the Mental Retardation Research Center of this same University, he returned to the University of Chile where he became Chairman of the Morphology Program at the Institute for Biomedical Sciences. In 2002, he moved to the Department of Psychiatry at the Medical School of the "Pontificia Universidad Católica de Chile", where he directs the Center for Neurobiological Studies (http://www.neuro.cl) and has been recently appointed as Full Professor. He has published some 70 ISI articles and 15 book chapters of neuroanatomy, comparative neurobiology and cognitive neuroscience.  Diego Cosmelli obtained in 2004 his PhD in Cognitive Science from the École Polytechnique, Palaiseau, France, studying the relation between phenomenological accounts, signal analysis methods and neurodynamical patterns during binocular rivalry. After a postdoctoral work on enactive approaches to consciousness at York University in Toronto, Canada, he returned to Chile. He is an Associate Researcher at the Center for Neurobiological Studies of the Psychiatry Dep. at the P. Universidad Católica de Chile. Since March 2008 he is Associate Professor of the School of Psychology of the same university. His current research is centered on the relation between biological organization, sensorimotor processes and the dynamics of human experience. Back cover text In addition to asking what attention actually is, decomposing and analyzing its varieties or revealing its neurobiological mechanisms, a full-fledged theory of attention must consider its workings in the context of motivated, goal-directed and environmentally constrained organisms. The essays compiled in this volume are aimed at making a contribution towards this end. Specifically, the main conclusion that can be drawn is that fundamental links exist between attention and two key processes that are crucial for adapted conduct: goal-directed behavior and cognitive control. Importantly, both the mechanisms underlying these processes, and the actual relations that exist between them, can and must be explored at multiple levels, including neurodynamical, neurochemical, evolutionary and clinical. In doing so, it is apparent that several methodological challenges arise which are worth considering and pursuing, particularly when an ecological take on these questions seems ever more necessary. The reader will find here an invitation to explore these numerous connections, through a selection of contributions that range from basic mechanisms of attention at the neuronal level to developmental aspects of cognitive control and its impairments.